Start Submission Become a Reviewer

Reading: Medicines used in pregnancy, childbirth and lactation in a teaching hospital in Lagos, Nigeria

Download

A- A+
dyslexia friendly

Research Article

Medicines used in pregnancy, childbirth and lactation in a teaching hospital in Lagos, Nigeria

Authors:

Kazeem A Oshikoya ,

Department of Pharmacology, Lagos Sate University College of Medicine, Ikeja, Lagos, NG
X close

Ireti O Akionla,

Department of Obstetrics and Gynaecology, Lagos State University College of Medicine, Ikeja, Lagos, NG
X close

Idowu O Senbanjo,

Paediatrics Department, Lagos State University College of Medicine, Ikeja, Lagos, NG
X close

Ibrahim A Oreagba,

Department of Pharmacology, College of Medicine, University of Lagos, Idiaraba, Lagos, NG
X close

Olayinka O Ogunleye

Department of Pharmacology, Lagos Sate University College of Medicine, Ikeja, Lagos, NG
X close

Abstract

Objective: Pharmacotherapy during pregnancy, childbirth and lactation is very challenging because only a few medicines have been specifically tested for safety and efficacy during pregnancy. This study aimed to evaluate the pattern of medicines prescribed and their risk categories during pregnancy, childbirth and lactation.

Methods: We performed a retrospective audit of the case files of registered pregnant women who received antenatal care, delivered their babies, and followed up postnatally for a period of six weeks at the Obstetrics and Gynaecology Department of the Lagos State University Teaching Hospital (LASUTH), between 1st July and 31st December 2007. The demographic and obstetric data of the patients, and the medications prescribed during pregnancy, childbirth and pueperium, were extracted.

Results: Altogether, 1536 (95.8%) case files were analysed. The median age of the patients was 29 (IQR: 27-32) years; their parity was between 0 and 5. Most of the patients were ≤30 years old (64.6%), nulliparous (70.3%), booked in the second trimester (54.2%), and had spontaneous vertex delivery (67.7%). ATC group B (1577; 48.6%), followed by ATC group N (448; 13.8%), were the most frequently prescribed medicines during pregnancy. Eighteen (39.1%) different types of medicines prescribed during pregnancy were in category C risk. ATC group G medicines (65.4%) were considerably prescribed in labour. Excluding haematinics, ATC group J medicines (42.2%) were often prescribed during lactation.

Conclusions: There was considerable use of medicine during pregnancy, childbirth and lactation in this study. Further studies are recommended to guide prophylactic use of antibiotics after uneventful normal childbirth.

DOI: http://dx.doi.org/10.4038/sljog.v34i3.4881

Sri Lanka Journal of Obstetrics and Gynaecology 2012; 34: 84-98

DOI: http://doi.org/10.4038/sljog.v34i3.4881
How to Cite: Oshikoya, K.A. et al., (2012). Medicines used in pregnancy, childbirth and lactation in a teaching hospital in Lagos, Nigeria. Sri Lanka Journal of Obstetrics and Gynaecology. 34(3), pp.84–98. DOI: http://doi.org/10.4038/sljog.v34i3.4881
558
Views
676
Downloads
Published on 05 Nov 2012.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus