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Case Reports

Glassy cell carcinoma (GCC) of uterine cervix

Authors:

Rahat Hadi ,

Department of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences (Dr RMLIMS), Vibhuti Khand, Gomti Nagar, Lucknow, Uttar Pradesh, IN
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Milind Kumar,

Department of Radiation Oncology, Dr B R A, Institute Rotary Cancer Hospital (IRCH), IN
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Sushmita Pat,

Department of Radiation Oncology, Dr B R A, Institute Rotary Cancer Hospital (IRCH), IN
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Prasenjit Das,

Department of Pathology, All India Institute of Medical Sciences (AIIMS), New Delhi, IN
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Arvind Vaid,

Department of Gynecology and Obstetrics, All India Institute of Medical Sciences (AIIMS), New Delhi, IN
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Siddhartha Datta Gupta,

Department of Pathology, All India Institute of Medical Sciences (AIIMS), New Delhi, IN
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BK Mohanti

Department of Radiation Oncology, Dr B R A, Institute Rotary Cancer Hospital (IRCH), IN
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Abstract

Glassy cell carcinoma (GCC) is a rare clinical entity involving uterine cervix with aggressive course and relatively poor prognosis. The most common presentation is abnormal bleeding or discharge per vaginum of recent origin. Histologically it is diagnosed by characteristic "Glassy" cells. All the three modalities (i.e. surgery, radiotherapy and chemotherapy) have been tried in various clinical settings, showing different clinical outcome. The common consensus regarding diagnosis and optimal treatment modalities is yet to emerge. The case presented here not only represents a rare histopathological diagnosis, but also reemphasizes the importance of Her2 neu immunostains as a bad prognostic marker.

Key words: glassy cell carcinoma; radiotherapy; Her2 neu; cervix.

DOI: http://dx.doi.org/10.4038/sljog.v33i2.4010

Sri Lanka Journal of Obstetrics and Gynaecology 2011; 33: 65-67

DOI: http://doi.org/10.4038/sljog.v33i2.4010
How to Cite: Hadi, R. et al., (2012). Glassy cell carcinoma (GCC) of uterine cervix. Sri Lanka Journal of Obstetrics and Gynaecology. 33(2), pp.65–67. DOI: http://doi.org/10.4038/sljog.v33i2.4010
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Published on 23 Jan 2012.
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