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Research Article

Leukocyte count on admission as a predictor of clinical outcome in the expectant management for women with preterm prelabor rupture of membranes

Authors:

Deeksha Pandey ,

Department of Obstetrics and Gynaecology, Kasturba Hospital, Manipal, IN
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Saurav Bhagat,

Department of Obstetrics and Gynaecology, Kasturba Hospital, Manipal, IN
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Vidhi Vanya,

Department of Obstetrics and Gynaecology, Kasturba Hospital, Manipal, IN
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VS Binu,

Department of Obstetrics and Gynaecology, Kasturba Hospital, Manipal, IN
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Muralidhar Pai,

Department of Obstetrics and Gynaecology, Kasturba Hospital, Manipal, IN
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Pratap Kumar

Department of Obstetrics and Gynaecology, Kasturba Hospital, Manipal, IN
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Abstract

Objective: We hypothesized that a single value of leukocyte count, on admission might be a helpful predictor to prognosticate the clinical outcome and plan the management (early delivery versus conservative management) in patients presenting with pre term pre-labour rupture of membranes (PPROM).

Design: Observational study.

Setting: This study was conducted in a tertiary care centre.

Population or sample: 127 pregnancies complicated with PPROM.

Method: A novel scoring system was devised depending upon the final clinical performance. Main outcome measure: Adverse fetal, neonatal and maternal outcome.

Result: Based on the score cut off for the total leukocyte count was calculated to prognosticate the outcome. Leukocyte count of 15,850/mm3, at the time of admission was found to be able to predict the clinical outcome with a sensitivity of 85.7% and specificity of 87.6%, in a case of PPROM. Whereas the individual components of differential leukocyte counts were found to be not of much help in this regard.

Conclusion: Leukocyte count of 15,850/mm3 at admission can be used to prognosticate outcome in pregnancies complicated with PPROM.

Key words: preterm prelabor rupture of membranes; total leukocyte count; differential count; prematurity; infectious morbidity.

DOI: http://dx.doi.org/10.4038/sljog.v33i2.4006

Sri Lanka Journal of Obstetrics and Gynaecology 2011; 33: 51-55

DOI: http://doi.org/10.4038/sljog.v33i2.4006
How to Cite: Pandey, D. et al., (2012). Leukocyte count on admission as a predictor of clinical outcome in the expectant management for women with preterm prelabor rupture of membranes. Sri Lanka Journal of Obstetrics and Gynaecology. 33(2), pp.51–55. DOI: http://doi.org/10.4038/sljog.v33i2.4006
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Published on 23 Jan 2012.
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